Recombinant HIPK2 (1-640) Protein

<strong>Recombinant HIPK2 (1-640) Protein</strong>_x000D_ <strong>Catalog number:</strong> B2017530_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 50 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 69.5 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> PRO0593_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Conte A, Pierantoni GM. Update on the Regulation of HIPK1, HIPK2 and HIPK3 Protein Kinases by microRNAs Microrna. 2018;7(3):178-186._x000D_ 2: Wang Y, Marion Schneider E, Li X, Duttenhöfer I, Debatin K, Hug H. HIPK2 associates with RanBPM Biochem Biophys Res Commun. 2002 Sep 13;297(1):148-53._x000D_ 3: Agnew C, Liu L, Liu S, Xu W, You L, Yeung W, Kannan N, Jablons D, Jura N. The crystal structure of the protein kinase HIPK2 reveals a unique architecture of its CMGC-insert region J Biol Chem. 2019 Sep 13;294(37):13545-13559._x000D_ 4: Verdina A, Di Rocco G, Virdia I, Monteonofrio L, Gatti V, Policicchio E, Bruselles A, Tartaglia M, Soddu S. HIPK2-T566 autophosphorylation diversely contributes to UV- and doxorubicin-induced HIPK2 activation Oncotarget. 2017 Mar 7;8(10):16744-16754._x000D_ 5: Gatti V, Ferrara M, Virdia I, Matteoni S, Monteonofrio L, di Martino S, Diodoro MG, Di Rocco G, Rinaldo C, Soddu S. An Alternative Splice Variant of HIPK2 with Intron Retention Contributes to Cytokinesis Cells. 2020 Feb 20;9(2):484._x000D_ 6: Pierantoni GM, Fedele M, Pentimalli F, Benvenuto G, Pero R, Viglietto G, Santoro M, Chiariotti L, Fusco A. High mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth Oncogene. 2001 Sep 27;20(43):6132-41._x000D_ 7: Hofmann TG, Jaffray E, Stollberg N, Hay RT, Will H. Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification J Biol Chem. 2005 Aug 12;280(32):29224-32._x000D_ 8: Jin Y, Ratnam K, Chuang PY, Fan Y, Zhong Y, Dai Y, Mazloom AR, Chen EY, D'Agati V, Xiong H, Ross MJ, Chen N, Ma'ayan A, He JC. A systems approach identifies HIPK2 as a key regulator of kidney fibrosis Nat Med. 2012 Mar 11;18(4):580-8._x000D_ 9: Kaina B, Christmann M. DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas DNA Repair (Amst). 2019 Jun;78:128-141._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/25868975">10: Valente D, Bossi G, Moncada A, Tornincasa M, Indelicato S, Piscuoglio S, Karamitopoulou ED, Bartolazzi A, Pierantoni GM, Fusco A, Soddu S, Rinaldo C. HIPK2 deficiency causes chromosomal instability by cytokinesis failure and increases tumorigenicity Oncotarget. 2015 Apr 30;6(12):10320-34. </a>_x000D_ _x000D_ <strong>Products Related to Recombinant HIPK2 (1-640) Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>