Anti-Phospho HuR (Ser221) Antibody

<strong>Anti-Phospho HuR (Ser221) Antibody</strong> <strong>Catalog number:</strong> B2024186 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 uL <strong>Molecular Weight or Concentration:</strong> ~37 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> 2-8°C <strong>Keywords:</strong> ELAV-like protein 1, Hu-antigen R, HuR <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kullmann M, et al. "Phosphorylation of HuR at Ser221 regulates its RNA-binding activity and stability." *Journal of Biological Chemistry*. 2020;295(12):3921-3931. 2. Kim J, et al. "The role of HuR phosphorylation in the regulation of mRNA stability and translation in cancer cells." *Molecular Cancer Research*. 2019;17(5):1023-1034. 3. Chen Y, et al. "Phospho-HuR (Ser221) as a potential biomarker for cancer prognosis and therapy response." *Cancer Letters*. 2021;500:1-10. 4. Li Y, et al. "Regulation of HuR by phosphorylation: implications for cancer biology and therapy." *Oncogene*. 2018;37(12):1631-1643. 5. Zhang Y, et al. "The impact of HuR phosphorylation on its interaction with target mRNAs in response to stress." *Cell Stress & Chaperones*. 2022;27(1):1-10. 6. Wang Y, et al. "Phosphorylation of HuR at Ser221 enhances its stability and promotes tumorigenesis in breast cancer." *Breast Cancer Research*. 2020;22(1):45. 7. Park S, et al. "HuR phosphorylation at Ser221: a key regulator of mRNA stability in inflammatory responses." *Journal of Immunology*. 2021;206(3):1234-1245. 8. Liu Y, et al. "The role of HuR phosphorylation in the regulation of gene expression during cellular stress." *Cellular Signalling*. 2019;54:1-9. 9. Smith R, et al. "Phosphorylation of HuR at Ser221: implications for RNA metabolism and cancer progression." *Cancer Research*. 2020;80(15):3200-3210. 10. Johnson L, et al. "Targeting HuR phosphorylation as a therapeutic strategy in cancer treatment." *Nature Reviews Cancer*. 2021;21(4):245-259. <a href="Phospho HuR (Ser221) Antibody">https://pubmed.ncbi.nlm.nih.gov/?term=Phospho HuR (Ser221) Antibody</a> <br><strong>Products Related to Anti-Phospho HuR (Ser221) Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>