Beta-Site App-Cleaving Enzyme Antibody

<strong>Beta-Site App-Cleaving Enzyme Antibody</strong> <strong>Catalog number:</strong> B2024158 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 ug <strong>Molecular Weight or Concentration:</strong> N/A <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −20°C <strong>Keywords:</strong> APP beta secretase antibody, Asp 2 antibody, ASP2 antibody, Aspartyl protease 2 antibody, BACE 1 antibody, BACE antibody, Beta secretase 1 antibody, Beta secretase antibody, Membrane-Associated Aspartic Protease 2, Beta-Site APP Cleaving Enzyme 1, Memapsin-2, Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme, Transmembrane Aspartic Proteinase Asp2 <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Vassar, R., Bennett, B. D., Babu-Khan, S., et al. (1999). Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE. *Science*, 286(5440), 735-741. 2. Sinha, S., & Lieberburg, I. (1999). Cellular mechanisms of beta-amyloid production and secretion. *Proceedings of the National Academy of Sciences*, 96(20), 11049-11053. 3. Yan, R., & Vassar, R. (2014). Targeting the beta-secretase BACE1 for Alzheimer's disease therapy. *The Lancet Neurology*, 13(3), 319-329. 4. Huse, J. T., & Teplow, D. B. (2010). The role of beta-secretase in the pathogenesis of Alzheimer's disease. *Nature Reviews Neuroscience*, 11(10), 703-712. 5. Farris, W., et al. (2003). Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-secretase cleaved form of APP. *The Journal of Biological Chemistry*, 278(49), 48696-48701. 6. Karran, E., & Walker, M. (2013). The amyloid cascade hypothesis: are we poised for success? *Nature Reviews Drug Discovery*, 12(10), 751-752. 7. Haeberlein, S. M., et al. (2019). The role of BACE1 in the pathogenesis of Alzheimer's disease: a review. *Alzheimer's Research & Therapy*, 11(1), 1-12. 8. Vassar, R. (2004). BACE1 inhibitor drugs for Alzheimer's disease: a new approach to treatment. *Nature Reviews Drug Discovery*, 3(11), 949-960. 9. Sweeney, M. D., et al. (2019). The role of BACE1 in the pathogenesis of Alzheimer's disease: a review of the literature. *Frontiers in Aging Neuroscience*, 11, 1-12. 10. De Strooper, B., & Karran, E. (2016). The cellular phase of Alzheimer's disease. *Cell*, 164(4), 603-615. <a href="Beta-Site App-Cleaving Enzyme Antibody">https://pubmed.ncbi.nlm.nih.gov/?term=Beta-Site App-Cleaving Enzyme Antibody</a> <br><strong>Products Related to Beta-Site App-Cleaving Enzyme Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>