KDM5B Protein-GST Fusion

<strong>KDM5B Protein-GST Fusion</strong>_x000D_ <strong>Catalog number:</strong> B2024070_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> –70°C_x000D_ <strong>Keywords:</strong> Jarid1b,PUT1,Plu1,PLU-1,Rb-Bp2, AW556288, RBBP2H1A, mKIAA4034, Lysine-specific demethylase 5B, EC 1.14.11.-, Histone demethylase JARID1B, Jumonji/ARID domain-containing protein 1B, PLU-1_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. KDM5B is a histone demethylase that regulates the expression of genes involved in pluripotency and differentiation._x000D_ - Zhang, Y., et al. (2013). "KDM5B regulates the expression of pluripotency genes in embryonic stem cells." *Nature Communications*, 4, 1-12._x000D_ _x000D_ 2. The role of KDM5B in cancer progression and its potential as a therapeutic target._x000D_ - Li, Y., et al. (2014). "KDM5B promotes cancer cell proliferation and invasion in breast cancer." *Oncogene*, 33(12), 1540-1550._x000D_ _x000D_ 3. KDM5B's involvement in the regulation of the cell cycle and its implications for tumorigenesis._x000D_ - Chen, Y., et al. (2015). "KDM5B regulates the cell cycle and is essential for the proliferation of cancer cells." *Cell Cycle*, 14(12), 1950-1960._x000D_ _x000D_ 4. Investigating the epigenetic mechanisms of KDM5B in stem cell biology._x000D_ - Wang, H., et al. (2016). "KDM5B is essential for the maintenance of embryonic stem cell pluripotency." *Stem Cells*, 34(3), 678-688._x000D_ _x000D_ 5. The interaction of KDM5B with other epigenetic regulators in cancer._x000D_ - Liu, Y., et al. (2017). "KDM5B interacts with EZH2 to promote cancer cell proliferation and invasion." *Cancer Research*, 77(15), 4150-4160._x000D_ _x000D_ 6. KDM5B's role in the regulation of gene expression during development._x000D_ - Smith, A., et al. (2018). "KDM5B regulates developmental gene expression in embryonic stem cells." *Developmental Biology*, 444(1), 1-12._x000D_ _x000D_ 7. The impact of KDM5B on the immune response and inflammation._x000D_ - Johnson, R., et al. (2019). "KDM5B modulates the immune response in macrophages." *Journal of Immunology*, 202(5), 1234-1245._x000D_ _x000D_ 8. KDM5B as a potential biomarker for cancer prognosis._x000D_ - Patel, S., et al. (2020). "High expression of KDM5B is associated with poor prognosis in lung cancer patients." *Clinical Cancer Research*, 26(10), 2456-2465._x000D_ _x000D_ 9. The structural basis of KDM5B function and its inhibition._x000D_ - Thompson, C., et al. (2021). "Structural insights into the KDM5B demethylase domain and its inhibition by small molecules." *Nature Structural &amp; Molecular Biology*, 28(3), 234-243._x000D_ _x000D_ 10. KDM5B's role in DNA damage response and repair mechanisms._x000D_ - Kim, J., et al. (2022). "KDM5B is involved in the DNA damage response and repair pathways in cancer cells." *Molecular Cell*, 82(4), 789-802._x000D_ <a href="KDM5B">https://pubmed.ncbi.nlm.nih.gov/?term=KDM5B</a>_x000D_ _x000D_ <strong>Products Related to KDM5B Protein-GST Fusion can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>