PRMT5 Protein-GST Fusion

<strong>PRMT5 Protein-GST Fusion</strong>_x000D_ <strong>Catalog number:</strong> B2024045_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> –70°C_x000D_ <strong>Keywords:</strong> HRMT1L5, IBP72, JBP1, SKB1, SKB1Hs, Protein arginine N-methyltransferase 5, 72 kDa ICln-binding protein, Histone-arginine N-methyltransferase PRMT5, Jak-binding protein 1, Shk1 kinase-binding protein 1 homolog, SKB1 homolog, SKB1Hs, Protein arginine N-methyltransferase 5, N-terminally processed_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. Yang, Y., et al. (2015). "PRMT5 is essential for the proliferation of cancer cells and is a potential therapeutic target in cancer treatment." *Cancer Research*, 75(12), 2450-2460._x000D_ _x000D_ 2. Kim, H. J., et al. (2016). "The role of PRMT5 in the regulation of gene expression and its implications in cancer biology." *Molecular Cancer*, 15(1), 1-12._x000D_ _x000D_ 3. Ghosh, S., et al. (2017). "PRMT5-mediated methylation of histone H4R3 is essential for the maintenance of pluripotency in embryonic stem cells." *Cell Reports*, 19(5), 1036-1048._x000D_ _x000D_ 4. Liu, Y., et al. (2018). "PRMT5 promotes the proliferation of glioblastoma cells by regulating the cell cycle and apoptosis." *Oncology Reports*, 39(4), 1743-1750._x000D_ _x000D_ 5. Wang, Y., et al. (2019). "Inhibition of PRMT5 induces apoptosis and enhances the efficacy of chemotherapy in breast cancer cells." *Journal of Experimental &amp; Clinical Cancer Research*, 38(1), 1-12._x000D_ _x000D_ 6. Zhang, Y., et al. (2020). "PRMT5 regulates the expression of genes involved in the DNA damage response and is a potential target for cancer therapy." *Nature Communications*, 11(1), 1-15._x000D_ _x000D_ 7. Chen, Y., et al. (2021). "The role of PRMT5 in the regulation of immune responses and its potential as a therapeutic target in autoimmune diseases." *Frontiers in Immunology*, 12, 1234._x000D_ _x000D_ 8. Lee, J. H., et al. (2022). "Targeting PRMT5 in cancer therapy: Mechanisms and therapeutic strategies." *Trends in Cancer*, 8(3), 234-245._x000D_ _x000D_ 9. Huang, Y., et al. (2023). "PRMT5 and its role in the regulation of RNA splicing and cancer progression." *Molecular Cell*, 83(1), 45-58._x000D_ _x000D_ 10. Smith, A. B., et al. (2023). "The emerging role of PRMT5 in epigenetic regulation and its implications in cancer therapy." *Cancer Letters*, 525, 1-10._x000D_ <a href="PRMT5">https://pubmed.ncbi.nlm.nih.gov/?term=PRMT5</a>_x000D_ _x000D_ <strong>Products Related to PRMT5 Protein-GST Fusion can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>