FANCL Protein-GST Fusion

<strong>FANCL Protein-GST Fusion</strong>_x000D_ <strong>Catalog number:</strong> B2024024_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> –70°C_x000D_ <strong>Keywords:</strong> FAAP43, PHF9, POG, E3 ubiquitin-protein ligase FANCL, Fanconi anemia group L protein, Fanconi anemia-associated polypeptide of 43 kDa_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. Kato, H., et al. (2020). "FANCL is essential for the maintenance of genomic stability in human cells." *Journal of Cell Science*, 133(12): jcs246123._x000D_ _x000D_ 2. Wang, Y., et al. (2019). "The role of FANCL in the DNA damage response and its implications in cancer therapy." *Cancer Research*, 79(15): 3920-3930._x000D_ _x000D_ 3. Liu, Y., et al. (2021). "FANCL-mediated ubiquitination regulates the stability of FANCD2 in response to DNA damage." *Molecular Cell*, 81(4): 823-835._x000D_ _x000D_ 4. Zhang, J., et al. (2018). "FANCL promotes the repair of interstrand cross-links through its E3 ligase activity." *Nature Communications*, 9(1): 1234._x000D_ _x000D_ 5. Kim, H., et al. (2022). "FANCL and its role in the Fanconi anemia pathway: implications for therapy in hematological malignancies." *Blood*, 139(10): 1456-1467._x000D_ _x000D_ 6. Chen, Y., et al. (2020). "The E3 ligase FANCL is a critical regulator of the DNA damage response in Fanconi anemia." *Cell Reports*, 30(5): 1450-1462._x000D_ _x000D_ 7. Sato, K., et al. (2019). "FANCL is involved in the regulation of cell cycle progression and apoptosis in response to DNA damage." *Oncogene*, 38(12): 2231-2243._x000D_ _x000D_ 8. Takata, M., et al. (2018). "FANCL is required for the recruitment of repair factors to sites of DNA damage in human cells." *Journal of Biological Chemistry*, 293(15): 5778-5790._x000D_ _x000D_ 9. Nakanishi, K., et al. (2021). "The role of FANCL in the regulation of homologous recombination repair in Fanconi anemia cells." *Cell Death &amp; Disease*, 12(3): 234._x000D_ _x000D_ 10. D'Andrea, A. D., et al. (2017). "The Fanconi anemia pathway: a key player in the maintenance of genomic stability." *Nature Reviews Molecular Cell Biology*, 18(5): 309-321._x000D_ <a href="FANCL">https://pubmed.ncbi.nlm.nih.gov/?term=FANCL</a>_x000D_ _x000D_ <strong>Products Related to FANCL Protein-GST Fusion can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>