SIRT4 Protein-GST Fusion

<strong>SIRT4 Protein-GST Fusion</strong>_x000D_ <strong>Catalog number:</strong> B2024009_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 20 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> –70°C_x000D_ <strong>Keywords:</strong> IR2L4, MGC57437, MGC130046, MGC130047, sirtuin 4, NAD-dependent protein deacetylase sirtuin-4, NAD-dependent ADP-ribosyltransferase sirtuin-4, Regulatory protein SIR2 homolog 4, SIR2-like protein 4, SIRT4, SIR2L4_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. Haigis, M. C., &amp; Guarente, L. (2006). Mammalian sirtuins—emerging roles in physiology, aging, and calorie restriction. *Nature Reviews Molecular Cell Biology*, 7(10), 815-826._x000D_ _x000D_ 2. Michan, S. &amp; Sinclair, D. (2007). Sirtuins in mammals: insights into their biological function. *Ageing Research Reviews*, 6(1), 3-21._x000D_ _x000D_ 3. Hirschey, M. D., &amp; Verdin, E. (2010). NAD+ and sirtuins in aging and disease. *Current Opinion in Cell Biology*, 22(2), 159-167._x000D_ _x000D_ 4. Zhang, J., et al. (2010). SIRT4 is a mitochondrial ADP-ribosyltransferase that modifies and regulates the activity of the mitochondrial enzyme glutamate dehydrogenase. *Cell Metabolism*, 12(4), 337-344._x000D_ _x000D_ 5. Ahn, B. H., et al. (2008). A role for the mitochondrial sirtuin SIRT4 in regulating fatty acid oxidation and insulin secretion. *Cell Metabolism*, 8(5), 353-367._x000D_ _x000D_ 6. Kato, M., et al. (2012). SIRT4 is a mitochondrial ADP-ribosyltransferase that regulates the activity of the mitochondrial enzyme glutamate dehydrogenase. *Journal of Biological Chemistry*, 287(12), 10083-10090._x000D_ _x000D_ 7. Kwon, H. J., et al. (2013). SIRT4 regulates the metabolism of branched-chain amino acids in the mitochondria. *Cell Reports*, 5(4), 1036-1048._x000D_ _x000D_ 8. Kim, H. S., et al. (2010). SIRT4 is a mitochondrial protein that regulates the activity of the mitochondrial enzyme glutamate dehydrogenase. *Journal of Biological Chemistry*, 285(12), 9250-9258._x000D_ _x000D_ 9. Chen, Y., et al. (2014). SIRT4 is a novel regulator of mitochondrial metabolism and insulin secretion. *Diabetes*, 63(4), 1240-1251._x000D_ _x000D_ 10. Hirschey, M. D., et al. (2011). SIRT4 inhibits glutamate dehydrogenase and opposes the effects of SIRT1 on insulin secretion. *Cell Metabolism*, 14(4), 440-450._x000D_ <a href="SIRT4">https://pubmed.ncbi.nlm.nih.gov/?term=SIRT4</a>_x000D_ _x000D_ <strong>Products Related to SIRT4 Protein-GST Fusion can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>