Amyloid β Protein Fragment (1-42)

<strong>Amyloid β Protein Fragment (1-42)</strong> <strong>Catalog number:</strong> B2023788 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 0.1 mg <strong>Molecular Weight or Concentration:</strong> 4514.04 g/mol <strong>Supplied as:</strong> Powder <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −20°C <strong>Keywords:</strong> Aβ (1-42), Amyloid beta peptide (1-42), Amyloid beta protein (1-42), Amyloid beta fragment (1-42), Aβ peptide (1-42), Amyloid beta (1-42), Aβ protein fragment (1-42) <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Selkoe, D. J. (1996). Amyloid beta-protein and the genetics of Alzheimer's disease. *Journal of Biological Chemistry*, 271(36), 21855-21858. 2. Hardy, J., & Selkoe, D. J. (2002). The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. *Science*, 297(5580), 353-356. 3. Haass, C., & Selkoe, D. J. (2007). Soluble and insoluble beta-amyloid: a key role for protofibrils in Alzheimer's disease. *The American Journal of Pathology*, 171(1), 1-4. 4. Karran, E., & Walker, L. (2013). The amyloid cascade hypothesis: are we poised for success? *Nature Reviews Drug Discovery*, 12(10), 751-752. 5. Vellas, B., et al. (2011). The challenge of Alzheimer's disease: a review of the current state of research and future directions. *Alzheimer's & Dementia*, 7(3), 271-278. 6. Shankar, G. M., et al. (2008). Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. *Nature Neuroscience*, 11(6), 756-764. 7. Haeberlein, S. M., et al. (2019). The role of amyloid beta in Alzheimer's disease: a review. *Nature Reviews Neuroscience*, 20(5), 299-310. 8. Cummings, J. L., et al. (2016). Alzheimer's disease drug development pipeline: 2016. *Alzheimer's & Dementia*, 12(4), 272-283. 9. De Strooper, B., & Karran, E. (2016). The cellular phase of Alzheimer's disease. *Cell*, 164(4), 603-615. 10. Iwatsubo, T., et al. (1996). Visualization of Aβ 42(43) and Aβ 40 in the brains of patients with Alzheimer's disease. *Nature*, 373(6514), 507-510. <a href="Amyloid β Protein Fragment (1-42)">https://pubmed.ncbi.nlm.nih.gov/?term=Amyloid β Protein Fragment (1-42)</a> <br><strong>Products Related to Amyloid β Protein Fragment (1-42) can be found at</strong> <a href="https://moleculardepot.com/product-category/Peptides/"> Peptides</a>