Alk Protein, Active

<strong>Alk Protein, Active</strong>_x000D_ <strong>Catalog number:</strong> B2023626_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 63.8 kDa_x000D_ <strong>Supplied as:</strong> Resin_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -70°C_x000D_ <strong>Keywords:</strong> Anaplastic lymphoma kinase_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. You L., Wang Z., Li H., &amp; Shou J. (2015). The role of STAT3 in autophagy. *Autophagy*, 11(5), 729-39._x000D_ _x000D_ 2. Skoulidis F. &amp; Heymach J.V. (2019). Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy. *Nat Rev Cancer*, 19(9), 495-509._x000D_ _x000D_ 3. Tulpule A., Guan J., Neel D.S., Allegakoen H.R. (2001). Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules. *Cell*, 184(10), 2649-2664._x000D_ _x000D_ 4. Chen D, Zhao M, &amp; Mundy GR.. (2004). Bone morphogenetic proteins. *Growth Factors*, 22(4), 233-41._x000D_ _x000D_ 5. Rybarczyk-Kasiuchnicz A, Ramlau R, &amp; Stencel K.. (2021). Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma. *Int J Mol Sci*, 106(4), 473-481._x000D_ _x000D_ 6. Xu Z., Pan Z., Jin Y., &amp; Gao Z. (2024). Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion. *Autophagy*, 20(2), 416-436._x000D_ _x000D_ 7. Reshetnyak A.V., Rossi P., Myasnikov A.G., Sowaileh M. (2021). Mechanism for the activation of the anaplastic lymphoma kinase receptor. *Nature*, 600(7887), 153-157._x000D_ _x000D_ 8. Rikova K., Guo A., Zeng Q., &amp; Possemato A. (2007). Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. *Cell*, 131(6), 1190-203._x000D_ _x000D_ 9. Chuang T.P., Lai W.Y., Gabre J.L., &amp; Lind D.E. (2023). ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. *Proc Natl Acad Sci U S A*, 120(8), e2216479120._x000D_ _x000D_ 10. Li T., Stayrook S.E., Tsutsui Y., &amp; Zhang J. (2021). Structural basis for ligand reception by anaplastic lymphoma kinase. *Nature*, 600(7887), 148-152._x000D_ <a href="Alk Protein, Active">https://pubmed.ncbi.nlm.nih.gov/?term=Alk Protein, Active</a>_x000D_ _x000D_ <strong>Products Related to Alk Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>