Diethyl pyridine-2,4-dicarboxylate
Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].
Product Specifications
CAS Number
41438-38-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/diethyl-pyridine-2-4-dicarboxylate.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : ≥ 20mg/mL
Smiles
CCOC(=O)C1=CC(=NC=C1)C(=O)OCC
Molecular Formula
C11H13NO4
Molecular Weight
223.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Tschank G, et al. Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor. Biochem J. 1991 Apr 15;275 (Pt 2) (Pt 2) :469-76.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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