Diethyl pyridine-2,4-dicarboxylate

Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].

Product Specifications

CAS Number

[41438-38-4]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Intermediate

Type

Reference compound

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/diethyl-pyridine-2-4-dicarboxylate.html

Concentration

10mM

Purity

99.81

Solubility

DMSO : ≥ 20mg/mL

Smiles

CCOC(=O)C1=CC(=NC=C1)C(=O)OCC

Molecular Formula

C11H13NO4

Molecular Weight

223.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Tschank G, et al. Inhibition of prolyl hydroxylation and procollagen processing in chick-embryo calvaria by a derivative of pyridine-2,4-dicarboxylate. Characterization of the diethyl ester as a proinhibitor. Biochem J. 1991 Apr 15;275 (Pt 2) (Pt 2) :469-76.