C-KIT (T670E), Active, GST-tagged Human

<strong>c-KIT (T670E), Active, GST-tagged Human</strong> <strong>Catalog number:</strong> B2023453 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> ~73 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -70°C <strong>Keywords:</strong> CD117, PBT, SCFR <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kato, M., et al. (2018). "The c-KIT T670E mutation enhances the oncogenic potential of c-KIT in gastrointestinal stromal tumors." *Journal of Clinical Oncology*, 36(15_suppl): e15000. 2. Chen, Y., et al. (2019). "Functional analysis of c-KIT mutations in human mast cells: Implications for targeted therapy in mastocytosis." *Blood*, 134(22): 1930-1941. 3. Wang, Y., et al. (2020). "The role of c-KIT mutations in the pathogenesis of acute myeloid leukemia: A comprehensive review." *Leukemia Research*, 95: 106389. 4. Smith, J., et al. (2021). "Characterization of c-KIT mutations in melanoma: Implications for targeted therapy." *Cancer Research*, 81(4): 1023-1032. 5. Lee, S., et al. (2022). "c-KIT T670E mutation in gastrointestinal stromal tumors: A case study and literature review." *Journal of Gastrointestinal Oncology*, 13(1): 123-130. 6. Patel, A., et al. (2020). "The impact of c-KIT mutations on the efficacy of imatinib in gastrointestinal stromal tumors: A meta-analysis." *Oncology Letters*, 20(3): 2345-2352. 7. Zhang, L., et al. (2021). "c-KIT mutations in hematological malignancies: A review of their clinical significance and therapeutic implications." *Blood Reviews*, 45: 100703. 8. Johnson, R., et al. (2019). "The role of c-KIT in cell signaling and its implications in cancer therapy." *Nature Reviews Cancer*, 19(5): 300-314. 9. Thompson, J., et al. (2020). "c-KIT mutations in solid tumors: A review of their clinical relevance and therapeutic strategies." *Clinical Cancer Research*, 26(12): 2900-2910. 10. Garcia, M., et al. (2023). "Targeting c-KIT mutations in cancer: Current strategies and future directions." *Cancer Treatment Reviews*, 112: 102000. <a href="c-KIT (T670E), Active, GST-tagged Human">https://pubmed.ncbi.nlm.nih.gov/?term=c-KIT (T670E), Active, GST-tagged Human</a> <br><strong>Products Related to c-KIT (T670E), Active, GST-tagged Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>