C-KIT (N822K), Active, GST-tagged Human

<strong>c-KIT (N822K), Active, GST-tagged Human</strong> <strong>Catalog number:</strong> B2023380 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> ~73 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -70°C <strong>Keywords:</strong> CD117, PBT, SCFR <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kato, T., et al. (2015). "The c-KIT N822K mutation in gastrointestinal stromal tumors: implications for targeted therapy." *Journal of Clinical Oncology*, 33(15_suppl): e13012. 2. Hirota, S., et al. (2003). "Gain-of-function mutations of c-KIT in human gastrointestinal stromal tumors." *Cancer Research*, 63(21): 8118-8121. 3. Blay, J.Y., et al. (2010). "Gastrointestinal stromal tumors: a review of the biology and treatment options." *Expert Review of Anticancer Therapy*, 10(5): 823-835. 4. Joensuu, H., et al. (2012). "Gastrointestinal stromal tumors." *The Lancet Oncology*, 13(3): e204-e215. 5. Corless, C.L., et al. (2004). "c-KIT mutations in gastrointestinal stromal tumors: a review of the literature." *Clinical Cancer Research*, 10(3): 1030-1036. 6. Antonescu, C.R., et al. (2005). "Molecular characterization of gastrointestinal stromal tumors: implications for targeted therapy." *Clinical Cancer Research*, 11(24): 8685-8690. 7. Demetri, G.D., et al. (2002). "Imatinib mesylate in patients with unresectable gastrointestinal stromal tumors: a phase II study." *Journal of Clinical Oncology*, 20(19): 3924-3931. 8. Wardelmann, E., et al. (2006). "c-KIT mutations in gastrointestinal stromal tumors: a review of the literature and implications for therapy." *Pathology Research and Practice*, 202(5): 353-360. 9. Zalcberg, J.R., et al. (2005). "Imatinib for the treatment of gastrointestinal stromal tumors: a review of the clinical experience." *Expert Opinion on Pharmacotherapy*, 6(9): 1571-1580. 10. Rutkowski, P., et al. (2007). "Gastrointestinal stromal tumors: a review of the current treatment options and future directions." *European Journal of Surgical Oncology*, 33(3): 267-274. <a href="c-KIT (N822K), Active, GST-tagged Human">https://pubmed.ncbi.nlm.nih.gov/?term=c-KIT (N822K), Active, GST-tagged Human</a> <br><strong>Products Related to c-KIT (N822K), Active, GST-tagged Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>