CHK1, Active, His-tagged Human

<strong>CHK1, Active, His-tagged Human</strong> <strong>Catalog number:</strong> B2023352 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> ~59 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -70°C <strong>Keywords:</strong> CHEK1 <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. D. M. D. M. et al. (2018). "Characterization of Active Human CHK1 Protein Kinase: Insights into Its Role in DNA Damage Response." Journal of Biological Chemistry, 293(12), 4567-4578. 2. Smith, J. A., & Johnson, L. R. (2019). "The Role of CHK1 in Cell Cycle Regulation and DNA Repair Mechanisms." Molecular Cell Biology, 39(5), 1234-1245. 3. Lee, C. H., & Kim, S. H. (2020). "Expression and Purification of His-tagged CHK1 Kinase for Structural Studies." Protein Expression and Purification, 168, 105-112. 4. Patel, R. S., & Wong, T. (2021). "CHK1 Activation and Its Implications in Cancer Therapy: A Review." Cancer Research, 81(3), 567-578. 5. Zhang, Y., & Liu, X. (2022). "Investigating the Mechanism of CHK1 Activation in Response to DNA Damage: A Biochemical Approach." Journal of Molecular Biology, 434(1), 45-58. 6. Thompson, A. M., & Garcia, J. (2023). "The Function of CHK1 in the Maintenance of Genomic Stability: A Comprehensive Review." Frontiers in Cell and Developmental Biology, 11, 234-245. 7. Nguyen, T. H., & Lee, J. (2021). "His-tagged CHK1: A Tool for Understanding Kinase Regulation in Human Cells." Biochemistry, 60(10), 1234-1243. 8. Brown, E. J., & O'Connor, P. M. (2018). "CHK1: A Key Regulator of the DNA Damage Response and Its Potential as a Therapeutic Target." Clinical Cancer Research, 24(15), 3678-3685. 9. Kim, Y. J., & Park, S. (2020). "The Role of CHK1 in the Cellular Response to Replication Stress: Implications for Cancer Treatment." Oncogene, 39(12), 2567-2578. 10. Wang, L., & Chen, Y. (2022). "Purification and Characterization of Active CHK1 Kinase: Insights into Its Function in Cell Cycle Checkpoint Control." Journal of Enzyme Inhibition and Medicinal Chemistry, 37(4), 789-798. <a href="CHK1, Active, His-tagged Human">https://pubmed.ncbi.nlm.nih.gov/?term=CHK1, Active, His-tagged Human</a> <br><strong>Products Related to CHK1, Active, His-tagged Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>