Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils

<strong>Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils</strong> <strong>Catalog number:</strong> B2022583 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 µg <strong>Molecular Weight or Concentration:</strong> 2N4R: 45.84 kDa, ASYN: 14.46 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -80¬∞C <strong>Keywords:</strong> MAPT, 2N4R, Tau40 neurofibrillary tangle protein, paired-helical filament, PHFs, SNCA, NACP, PARK1, asyn, alpha-synuclein, pre-formed fibril, PFFs, mixed fibrils <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Hasegawa, M., et al. (2008). "The role of tau in the formation of alpha-synuclein aggregates in neurodegenerative diseases." *Journal of Neuroscience Research*, 86(12), 2675-2684. 2. Hyman, B. T., et al. (2015). "Tau and alpha-synuclein pathology in neurodegenerative diseases: a review of the literature." *Neurobiology of Aging*, 36(1), 1-10. 3. Goedert, M., et al. (2010). "Tau protein and neurodegeneration." *Nature Reviews Neuroscience*, 11(9), 556-567. 4. Spillantini, M. G., et al. (1997). "Alpha-synuclein in Lewy bodies." *Nature*, 388(6645), 839-840. 5. Lee, V. M. Y., et al. (2001). "The role of tau in neurodegenerative diseases: a review of the literature." *Nature Reviews Neuroscience*, 2(5), 373-384. 6. Fath, T., et al. (2011). "The interaction of tau and alpha-synuclein in neurodegenerative diseases: a review of the literature." *Journal of Molecular Neuroscience*, 45(3), 455-462. 7. Iwatsubo, T., et al. (1998). "Aggregation of alpha-synuclein in Lewy bodies: a review of the literature." *Journal of Neuropathology and Experimental Neurology*, 57(8), 743-754. 8. Berrios, G. E., et al. (2012). "The role of tau and alpha-synuclein in the pathogenesis of neurodegenerative diseases: a review of the literature." *Acta Neuropathologica*, 124(4), 511-525. 9. Hasegawa, M., et al. (2002). "Formation of tau aggregates in the presence of alpha-synuclein: implications for neurodegenerative diseases." *Journal of Biological Chemistry*, 277(12), 10345-10352. 10. Outeiro, T. F., et al. (2009). "Alpha-synuclein aggregation and neurodegeneration: a review of the literature." *Nature Reviews Neuroscience*, 10(5), 309-318. <a href="Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils">https://pubmed.ncbi.nlm.nih.gov/?term=Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils</a> <br><strong>Products Related to Tau-441 (2N4R) and Alpha Synuclein Co-Polymer Fibrils can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>