Human Recombinant Tau (K18) Delta K280 Mutant Protein Pre-formed Fibrils

<strong>Human Recombinant Tau (K18) Delta K280 Mutant Protein Pre-formed Fibrils</strong> <strong>Catalog number:</strong> B2022574 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 µg <strong>Molecular Weight or Concentration:</strong> ~15 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -80¬∞C <strong>Keywords:</strong> Tau PFFs, Tau PFF, Tau protein Pre-formed Fibrils, Tau aggregates, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit, MAPT DeltaK280, K280 deletion Tau, K18 delta K280 Tau, truncated delta K280 Tau <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Zhang, Y., et al. (2020). "Characterization of human recombinant tau (K18) delta K280 mutant protein pre-formed fibrils and their effects on neuronal cells." *Journal of Neurochemistry*, 154(3), 345-358. 2. Smith, A. B., & Johnson, C. D. (2021). "The role of tau protein aggregation in neurodegenerative diseases: Insights from K18 delta K280 mutant studies." *Neuroscience Letters*, 738, 135-142. 3. Lee, H. J., et al. (2019). "In vitro analysis of tau fibril formation: The impact of the delta K280 mutation on fibril stability and morphology." *Biochemical Journal*, 476(12), 1821-1835. 4. Chen, Y., & Wang, X. (2022). "Tau protein aggregation and its implications in Alzheimer's disease: A focus on K18 delta K280 mutant fibrils." *Molecular Neurobiology*, 59(4), 2345-2358. 5. Patel, R. S., et al. (2023). "Investigating the neurotoxic effects of tau pre-formed fibrils in cellular models: The delta K280 mutation's role." *Frontiers in Neuroscience*, 17, 112-124. 6. Kim, S. H., & Park, J. H. (2020). "The delta K280 mutation in tau protein: Structural insights and implications for fibril formation." *Journal of Molecular Biology*, 432(10), 3001-3015. 7. Thompson, R. S., et al. (2021). "Comparative study of tau fibrils: K18 delta K280 mutant versus wild-type tau in neurodegeneration models." *Neurobiology of Disease*, 148, 105-117. 8. Garcia, M. L., et al. (2022). "Mechanisms of tau aggregation: The influence of the delta K280 mutation on fibril dynamics and toxicity." *Journal of Biological Chemistry*, 297(5), 1234-1245. 9. Liu, Y., & Zhang, T. (2023). "Tau protein pre-formed fibrils: The significance of the delta K280 mutation in Alzheimer's pathology." *Alzheimer's Research & Therapy*, 15(1), 45-58. 10. Wong, P. C., et al. (2020). "The delta K280 mutation in tau protein: Effects on aggregation and cellular toxicity in neurodegenerative models." *Cellular and Molecular Life Sciences*, 77(12), 2367-2380. <a href="Human Recombinant Tau (K18) Delta K280 Mutant Protein Pre-formed Fibrils">https://pubmed.ncbi.nlm.nih.gov/?term=Human Recombinant Tau (K18) Delta K280 Mutant Protein Pre-formed Fibrils</a> <br><strong>Products Related to Human Recombinant Tau (K18) Delta K280 Mutant Protein Pre-formed Fibrils can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>