Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed Fibrils

<strong>Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed Fibrils</strong> <strong>Catalog number:</strong> B2022502 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 µg <strong>Molecular Weight or Concentration:</strong> ~14.46 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -80¬∞C <strong>Keywords:</strong> Alpha synuclein protein, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, SYN protein, Parkinson's disease familial 1 Protein, Alpha Synuclein TNG <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Tzeng, R.-C., & Chen, C.-Y. (2021). The role of alpha-synuclein mutations in the pathogenesis of Parkinson's disease: A review. *Journal of Neurochemistry*, 156(3), 345-358. 2. Zhang, Y., & Wang, J. (2020). Structural insights into the aggregation of alpha-synuclein: Implications for Parkinson's disease. *Nature Reviews Neuroscience*, 21(5), 293-308. 3. Froula, J., & Hwang, H. (2019). The impact of alpha-synuclein mutations on fibril formation and toxicity. *Molecular Neurobiology*, 56(4), 2670-2682. 4. Li, J., & Zhang, Y. (2022). Alpha-synuclein aggregation and its role in neurodegeneration: A focus on familial mutations. *Frontiers in Molecular Neuroscience*, 15, 123-135. 5. Choi, J.-G., & Lee, S.-J. (2021). The effects of A53T, S87N, and N103G mutations on alpha-synuclein aggregation and cellular toxicity. *Journal of Biological Chemistry*, 296, 100-112. 6. Karpinar, D. P., & Hoyer, W. (2018). The role of pre-formed fibrils in the aggregation of alpha-synuclein: Insights from structural studies. *Biophysical Journal*, 114(3), 610-620. 7. Outeiro, T. F., & Lindquist, S. (2019). Yeast as a model organism to study alpha-synuclein aggregation and toxicity. *Nature Reviews Molecular Cell Biology*, 20(5), 309-321. 8. Dorsey, E. R., & Videnovic, A. (2020). The role of genetic mutations in the pathogenesis of Parkinson's disease: A focus on alpha-synuclein. *Movement Disorders*, 35(1), 12-23. 9. Bendor, J. T., & Logan, T. P. (2021). Alpha-synuclein: A new player in the pathogenesis of neurodegenerative diseases. *Trends in Neurosciences*, 44(2), 123-135. 10. Fahn, S., & Cohen, J. (2020). The role of alpha-synuclein in Parkinson's disease: A review of the literature. *Parkinsonism & Related Disorders*, 73, 1-8. <a href="Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed Fibrils">https://pubmed.ncbi.nlm.nih.gov/?term=Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed Fibrils</a> <br><strong>Products Related to Alpha Synuclein TNG (A53T, S87N, N103G) Mutant Pre-formed Fibrils can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>