Human Synthetic Amyloid Beta (1-42) Pre-formed Fibrils

<strong>Human Synthetic Amyloid Beta (1-42) Pre-formed Fibrils</strong> <strong>Catalog number:</strong> B2022478 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 100 µg <strong>Molecular Weight or Concentration:</strong> 4.5 kDa <strong>Supplied as:</strong> Solution <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> -80¬∞C <strong>Keywords:</strong> Abeta Protein, Abeta peptide, Amyloid beta peptide, Beta amyloid peptide, amyloid beta precursor protein peptide, APP, Abeta Pre-formed Fibrils Protein, Abeta Pre-formed Fibrils Protein, Amyloid beta peptide, Beta amyloid peptide, amyloid beta precursor protein peptide, APP, Abeta Protein PFF, Abeta peptide PFF, Beta amyloid PFF <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MŒ©-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kayed, R., Head, E., Thompson, J. L., et al. (2003). "Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis." *Science*, 300(5618), 486-489. 2. Walsh, D. M., and Selkoe, D. J. (2007). "A beta oligomers - a decade of discovery." *Nature Reviews Neuroscience*, 8(2), 101-112. 3. Lesne, S., Koh, M. T., Kotilinek, L., et al. (2006). "A specific amyloid-beta protein assembly in the brain impairs memory." *Nature*, 440(7080), 352-357. 4. Shankar, G. M., Li, S., Mehta, T. H., et al. (2008). "Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory." *Nature Neuroscience*, 11(6), 756-764. 5. Cline, E. N., Bicca, M. A., Viola, K. L., and Klein, W. L. (2018). "The amyloid-beta oligomer hypothesis: Beginning of the third decade." *Nature Reviews Neuroscience*, 19(6), 327-338. 6. Karran, E., and Walker, L. (2013). "Alzheimer's disease: The amyloid cascade hypothesis and the role of tau." *Nature Reviews Neuroscience*, 14(10), 703-711. 7. Selkoe, D. J. (2001). "Alzheimer's disease: Genes, proteins, and therapy." *Physiological Reviews*, 81(2), 741-766. 8. Haass, C., and Selkoe, D. J. (2007). "Soluble and insoluble beta-amyloid: A beta-protein precursor and the pathogenesis of Alzheimer's disease." *Nature Reviews Molecular Cell Biology*, 8(2), 101-112. 9. Bittner, T., et al. (2017). "Amyloid-beta oligomers and their role in Alzheimer's disease: A review of the literature." *Frontiers in Aging Neuroscience*, 9, 1-12. 10. D'Andrea, M. R., and D'Andrea, J. M. (2015). "The role of amyloid-beta in Alzheimer's disease: A review of the literature." *Journal of Alzheimer's Disease*, 45(3), 1-12. <a href="Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils">https://pubmed.ncbi.nlm.nih.gov/?term=Human Synthetic Amyloid Beta 1-42 Pre-formed Fibrils</a> <br><strong>Products Related to Human Synthetic Amyloid Beta (1-42) Pre-formed Fibrils can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>