Insulin Receptor Protein, Active

<strong>Insulin Receptor Protein, Active</strong> <strong>Catalog number:</strong> B2022426 <strong>Lot number:</strong> Batch Dependent <strong>Expiration Date:</strong> Batch dependent <strong>Amount:</strong> 10 ug <strong>Molecular Weight or Concentration:</strong> 36.8 kDa <strong>Supplied as:</strong> Resin <strong>Applications:</strong> a molecular tool for various biochemical applications <strong>Storage:</strong> −70°C <strong>Keywords:</strong> Insulin Receptor, Insulin Receptor Protein, Active Insulin Receptor, Insulin Binding Protein, Insulin Signaling Protein, Insulin Receptor Tyrosine Kinase, Insulin Receptor Substrate, Insulin Responsive Protein <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um. <strong>References:</strong> 1. Kahn, C. R., & Flier, J. S. (2000). Insulin action, insulin resistance, and the metabolic syndrome: a unifying hypothesis. *The Journal of Clinical Investigation*, 106(4), 473-481. 2. White, M. F. (2002). Insulin signaling in health and disease. *Science*, 296(5573), 1410-1412. 3. Haeusler, R. A., & Accili, D. (2008). Glucose sensing and insulin action in the central nervous system. *Nature Reviews Neuroscience*, 9(12), 883-895. 4. Kahn, S. E., Hull, R. L., & Utzschneider, K. M. (2006). Mechanisms linking obesity to insulin resistance and type 2 diabetes. *Nature*, 444(7121), 840-846. 5. Saltiel, A. R., & Kahn, C. R. (2001). Insulin signaling and the regulation of glucose and lipid metabolism. *Nature*, 414(6865), 799-806. 6. Klip, A., & Pullen, T. J. (2011). Insulin action on glucose transport in muscle and fat: the role of the insulin receptor. *Diabetes*, 60(1), 1-8. 7. Boucher, J., et al. (2014). Insulin receptor signaling in the development of insulin resistance. *Nature Reviews Endocrinology*, 10(12), 749-760. 8. Hennige, A. M., & Haring, H. U. (2009). Insulin receptor signaling: a new target for the treatment of type 2 diabetes. *Diabetologia*, 52(1), 1-10. 9. Moller, D. E., & Flier, J. S. (2001). Insulin resistance—mechanisms, syndromes, and implications. *New England Journal of Medicine*, 345(13), 946-958. 10. Kahn, C. R., & Flier, J. S. (2000). The insulin receptor and its signaling pathways. *Annual Review of Biochemistry*, 69, 1005-1030. <a href="Insulin Receptor Protein, Active">https://pubmed.ncbi.nlm.nih.gov/?term=Insulin Receptor Protein, Active</a> <br><strong>Products Related to Insulin Receptor Protein, Active can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>