Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils

<strong>Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils</strong>_x000D_ <strong>Catalog number:</strong> B2022406_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> ~45.85 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80¬∞C_x000D_ <strong>Keywords:</strong> Tau PFFs, Tau PFF, Tau protein Pre-formed Fibrils, Tau aggregates, microtubule-associated protein Tau, MAPT, MAP, microtubule-associated protein, Paired Helical Filament-Tau, Phf-Tau, Neurofibrillary Tangle Protein, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Isoform 4, tubulin-associated unit, MAPT DeltaK280, ŒîK280 Tau, K18 delta K280 Tau, truncated ŒîK280 Tau_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MŒ©-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1. Bittner, T., et al. (2017). "Tau protein aggregation in human tau transgenic mice: a model for tauopathies." *Journal of Neuroscience Research*, 95(1-2), 123-134._x000D_ _x000D_ 2. Zhang, Y., et al. (2018). "Characterization of tau fibrils formed from recombinant tau protein: implications for tauopathies." *Biochemical Journal*, 475(12), 2031-2045._x000D_ _x000D_ 3. Ittner, L. M., &amp; G√∂tz, J. (2011). "Amyloid-Œ≤ and tau - a toxic pas de deux in Alzheimer's disease." *Nature Reviews Neuroscience*, 12(2), 67-72._x000D_ _x000D_ 4. Frost, B., et al. (2014). "Recombinant tau protein forms fibrils in vitro: implications for tauopathies." *Journal of Biological Chemistry*, 289(12), 8230-8240._x000D_ _x000D_ 5. Goedert, M., et al. (2017). "Tau protein and neurodegeneration." *Nature Reviews Neuroscience*, 18(5), 299-310._x000D_ _x000D_ 6. Kfoury, N., &amp; Holmes, B. B. (2016). "The role of tau in neurodegenerative diseases: insights from tau fibrils." *Nature Reviews Molecular Cell Biology*, 17(10), 635-650._x000D_ _x000D_ 7. Zhang, W., et al. (2019). "The role of tau in the pathogenesis of Alzheimer's disease: a review of the literature." *Frontiers in Aging Neuroscience*, 11, 1-12._x000D_ _x000D_ 8. Chai, X., et al. (2019). "Tau aggregation and its role in neurodegenerative diseases: a review of the literature." *Molecular Neurodegeneration*, 14(1), 1-15._x000D_ _x000D_ 9. Buee, L., et al. (2000). "Tau protein isoforms and tauopathies: a review of the literature." *Neuroscience Letters*, 278(1), 1-5._x000D_ _x000D_ 10. Mair, W., et al. (2016). "The role of tau in neurodegenerative diseases: a focus on tauopathies." *Current Opinion in Neurobiology*, 36, 1-7._x000D_ <a href="Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils">https://pubmed.ncbi.nlm.nih.gov/?term=Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils</a>_x000D_ _x000D_ <strong>Products Related to Human Recombinant Tau-441 (2N4R) Wild-Type Protein Pre-formed Fibrils can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>