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Echistatin, α1 isoform

Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

5417.1

Molecular Formula

C217H341N71O74S9

Notes

Research use only, not for human use.

Receptor

——

CAS Number

154303-05-6

Available Sizes

Curated Selection

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