Echistatin, α1 isoform
Potent irreversible αVβ3 integrin antagonist (Ki = 0.27 nM) . Disrupts attachment of osteoclasts to bone and inhibits bone reabsorption (IC50 = 0.1 nM) . Prevents ADP-induced platelet aggregation via inhibition of glycoprotein IIb/IIIa (GpIIb/IIIa, αIIbβ3) receptors (IC50 = 30 nM) in vitro.
Product Specifications
CAS Number
154303-05-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
5417.1
Molecular Formula
C217H341N71O74S9
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Curated Selection
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