Cyclotraxin B
Antagonist of TrkB receptors; inhibits BDNF-induced TrkB activity (IC50 = 0.30 nM) . Allosterically alters TrkB receptor conformation but does not alter BDNF binding. Prevents BDNF-induced cold allodynia in mice. Also shown to exhibit putative anxiolytic properties in mice.
Product Specifications
CAS Number
1203586-72-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1200.36
Molecular Formula
C48H73N13O17S3
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
NBP3-08403PE 100 µL
Mouse Monoclonal ECM-1/Secretory Component P85 Antibody (rSPM217) [PE]
Ask
View Details 