CALP1
Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibiting Ca2+-mediated cytotoxicity and apoptosis (IC50 = 52 μM) . Shown to protect pancreatic acinar cells from gossypol induced necrosis. Inhibits VLA-5-mediated adhesion of mast cells to fibronectin in vitro and attenuates inflammatory cell influx in guinea pig lung in vivo.
Product Specifications
CAS Number
145224-99-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
842.09
Molecular Formula
C40H75N9O10
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6347650-01 0.2 mL
Sik1, CT (Sik1, Msk, Sik, Snf1lk, Serine/threonine-protein kinase SIK1, HRT-20, Myocardial SNF1-like kinase, Salt-inducible kinase 1, Serine/threonine-protein kinase SNF1-like kinase 1) (Biotin)
Ask
View Details 
MBS6347650-02 5x 0.2 mL
Sik1, CT (Sik1, Msk, Sik, Snf1lk, Serine/threonine-protein kinase SIK1, HRT-20, Myocardial SNF1-like kinase, Salt-inducible kinase 1, Serine/threonine-protein kinase SNF1-like kinase 1) (Biotin)
Ask
View Details 
