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HS 014

Potent and selective melanocortin MC4 receptor antagonist (Ki values are 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively) . Increases food intake in rats and nociception in mice following central administration in vivo. Also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus.

Product Specifications

CAS Number

207678-81-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

1563.77

Molecular Formula

C71H94N20O17S2

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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