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JKC 363

Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces formalin-induced pain in vivo.

Product Specifications

CAS Number

436083-30-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

1506.72

Molecular Formula

C69H91N19O16S2

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

Curated Selection

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