JKC 363
Potent and selective melanocortin MC4 receptor antagonist (IC50 values are 0.5 and 44.9 nM at MC4 and MC3 respectively) that antagonizes the effects of α-MSH. Suppresses thyrotropin-releasing hormone (TRH) release, attenuates food intake and reduces formalin-induced pain in vivo.
Product Specifications
CAS Number
436083-30-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1506.72
Molecular Formula
C69H91N19O16S2
Notes
Research use only, not for human use.
Receptor
——
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