KYL
EphA4 receptor tyrosine kinase inhibitor (Kd = 0.8 μM) ; inhibits EphA4-EphrinA5 interactions (IC50 = 6.34 μM) . Prevents AβO induced synaptic damage, dendritic spine loss and prevents the blocking of LTP in hippocampal CA3-CA1 transmissions. Exhibits a long half life in cell culture media (8 and 12 hours in PC3 and C2C12 media respectively) . Neuroprotective.
Product Specifications
CAS Number
676657-00-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1465.75
Molecular Formula
C74H108N14O17
Notes
Research use only, not for human use.
Receptor
——
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