K 41498
Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively) . Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration.
Product Specifications
CAS Number
434938-41-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
3632.26
Molecular Formula
C162H276N48O46
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
