Mambalgin 1
Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively) . Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Increases latency of withdrawal response in mouse tail-flick and paw-flick tests. Analgesic.
Product Specifications
CAS Number
1609937-15-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
6554.51
Molecular Formula
C272H429N85O84S10
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog