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Mambalgin 1

Selective ASIC1a inhibitor (IC50 values are 192 and 72 nM for human ASIC1a and ASIC1a/1b dimer, respectively) . Binds to closed/inactive channel. Selective for ASIC1a over ASIC2a, ASIC3, TRPV1, P2X2, 5-HT3, Nav1.8, Cav3.2 and Kv1.2 channels. Increases latency of withdrawal response in mouse tail-flick and paw-flick tests. Analgesic.

Product Specifications

CAS Number

1609937-15-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

6554.51

Molecular Formula

C272H429N85O84S10

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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