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MM 54

Potent apelin receptor antagonist (Ki = 82 nM; IC50 = 93 nM) . Antagonizes the inhibitory affect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Recuces tumor expansion and lengthens survival time in a mouse xenograft model of glioblastoma.

Product Specifications

CAS Number

1313027-43-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

1737.15

Molecular Formula

C70H121N29O15S4

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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