MEN 11270
Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3) ; conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5) .
Product Specifications
CAS Number
235082-52-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1299.56
Molecular Formula
C60H90N20O11S
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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