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MEN 11270

Peptide antagonist of the B2 bradykinin receptor (pKi = 10.3) ; conformationally constrained cyclized analog of HOE 140. Blocks hypotension and bronchoconstriction in vivo. Displays selectivity for B2 over 29 other receptors and ion channels (pIC50 < 5.5) .

Product Specifications

CAS Number

235082-52-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

1299.56

Molecular Formula

C60H90N20O11S

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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