NFAT inhibitor, Cell Permeable
NFAT inhibitor. Inhibits LPS or LPS plus IFN-γ-induced IL-12 p40, IL-12 p70, IL-23 and TNF secretion from bone marrow-derived macrophages (BMDMs) . Also attenuates NO production and Nos2 mRNA expression in LPS-stimulated BMDMs. Improves symptoms in a mouse model of colitis. Exhibits immunosuppressive effects; enhances graft survival in mice. Cell permeable.
Product Specifications
CAS Number
592517-80-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
3573.15
Molecular Formula
C147H259N67O36S
Notes
Research use only, not for human use.
Receptor
——
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