Orphanin FQ (1-11)

Peptide fragment containing amino acids 1-11 of Nociceptin. Potent agonist of the ORL1/KOR-3 receptor (Ki = 55 nM) ; displays no affinity for opioid receptors, including μ, δ, κ1 and κ3 receptors (Ki >1000 nM) . Displays analgesic properties in CD-1 mice.