ProTx III
Potent Nav1.7 blocker (IC50 = 2.5 nM) . Also inhibits Nav1.1, Nav1.2, Nav1.3 and Nav1.6 in the nanomolar range. Exhibits no effects on Cav channels or nAChR at 5 μM. Demonstrates analgesic activity in vivo; antagonizes effects of scorpion-venom toxin OD1 at Nav1.7.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
3802.41
Molecular Formula
C162H246N52O43S6
Notes
Research use only, not for human use.
Receptor
——
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