PUMA BH3
PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
3049.3
Molecular Formula
C128H202N42O43S
Notes
Research use only, not for human use.
Receptor
Bak
Available Sizes
Curated Selection
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