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PUMA BH3

PUMA BH3 is a p53 upregulated modulator of apoptosis (PUMA) BH3 domain peptide, acts as a direct activator of Bak, with a Kd of 26 nM.This is a PUMA BH3 domain peptide. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome C release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.

Product Specifications

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

3049.3

Molecular Formula

C128H202N42O43S

Notes

Research use only, not for human use.

Receptor

Bak

Available Sizes

Curated Selection

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