PACAP (1-38), human, ovine, rat TFA
PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM) . PACAP 1-38 (10-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
4648.28
Molecular Formula
C203H331N63O53S.C2HF3O2
Notes
Research use only, not for human use.
Receptor
IC50: 4 nM (PACAP type I receptor), 2 nM (PACAP type II receptor VIP1), and 1 nM (PACAP type II receptor VIP2)
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