R8-T198wt
Cell-permeable peptide inhibitor of Pim-1 kinase, derived from p27Kip1. Inhibits Pim-1 phosphorylation of p27Kip1 and Bad; induces cell cycle arrest (at G1) and apoptosis in DU145 prostate cancer cells. Also inhibits Pim-1-dependent growth of DU145 cells in vitro and in vivo. Displays no effect on the growth of normal prostate epithelial RPWE-1 cells at concentrations of 10 and 20 μM.
Product Specifications
CAS Number
2305815-72-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
2820.33
Molecular Formula
C111H211N59O26S
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Yyj5066-1mgEcoli 1 mg (E. coli)
Recombinant Mycobacterium Vanbaalenii cobQ Protein (aa 1-490)
Sign In for Pricing
View Details 
MBS6135400-01 0.1 mL
ASL (Arginosuccinase, Argininosuccinate Lyase, ASAL) APC
Sign In for Pricing
View Details MBS6135400-02 5x 0.1 mL
ASL (Arginosuccinase, Argininosuccinate Lyase, ASAL) APC
Sign In for Pricing
View Details