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ShK-Dap22

Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents) . Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4) . Suppresses T cell activation in vitro (IC50 < 500 pM) .

Product Specifications

CAS Number

220384-25-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

4012.7

Molecular Formula

C166H268N54O48S7

Notes

Research use only, not for human use.

Receptor

——

Available Sizes

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