ShK-Dap22
Extremely potent KV1.3 channel blocker (Kd = 23 pM for mKV1.3 currents) . Selective for KV1.3 over other mammalian potassium channels (IC50 values are 23, 1800, 10500, 37000 and 39000 pM for mKV1.3, mKV1.1, hKV1.6, mKV1.4 and rKV1.2 respectively, and >100000 pM for hKV1.5, mKV1.7, hKV3.1, rKV3.4 and hKCa4) . Suppresses T cell activation in vitro (IC50 < 500 pM) .
Product Specifications
CAS Number
220384-25-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
4012.7
Molecular Formula
C166H268N54O48S7
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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