Urantide
Selective and competitive urotensin-II (UT) receptor antagonist (pKB = 8.3) . Blocks hU-II induced contractions in thoracic aorta ex vivo. Exhibits no effect on noradrenaline or endothelin 1-induced contraction or on acetylcholine-induced relaxation. Behaves as a partial agonist in a calcium mobilization assay (in CHO cells expressing hUT receptors) .
Product Specifications
CAS Number
669089-53-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1075.26
Molecular Formula
C51H66N10O12S2
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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