QWF
Tripeptide substance P (SP) antagonist (IC50 = 90 μM) . Also inhibits binding of SP to Mas-related GPCR (MRGPR) X2. Inhibits SP-induced IgE-independent degranulation of mast cells in vitro. Inhibits compound 48/80-induced MRGPRX2 activation and scratching in mice in vivo.
Product Specifications
CAS Number
126088-82-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
697.78
Molecular Formula
C38H43N5O8
Notes
Research use only, not for human use.
Receptor
——
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