Cortistatin-14
Cortistatin 14 is a neuropeptide expressed in inhibitory neurons of the cerebral cortex. Depresses neuronal activity, and induces slow-wave sleep, likely through antagonism of acetylcholine. It is structurally and functionally similar to somatostatin 14. Competes with somatostatin 14 for binding of somatostatin receptors (IC50s=5, 0.09, 0.3, 0.2, and 0.3nM for receptors sst1-5, respectively) .
Product Specifications
CAS Number
186901-48-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
1720.03
Molecular Formula
C81H114N20O18S2
Notes
Research use only, not for human use.
Receptor
——
Available Sizes
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