N-Formyl-Met-Leu-Phe-Lys
N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.
Product Specifications
CAS Number
67247-11-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
565.73
Molecular Formula
C27H43N5O6S
Notes
Research use only, not for human use.
Receptor
EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)
Available Sizes
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