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N-Formyl-Met-Leu-Phe-Lys

N-Formyl-Met-Leu-Phe-Lys (fMLFK) is a peptide, acts as a potent and selective agonist of FPR1, with EC50s of 3.5 nM, 6.7 μM and 0.88 μM for FPR1, FPR2 and FPR2-D2817.32G, respectively.Chemotactic peptide (fMLFK) binds specifically to receptors on leukocyte membranes. Uptake of chemotactic peptides can contribute to quantitative assessment of neutrophils in localized inflammatory processes and is independent of associated edema formation or microcirculatory compromise.

Product Specifications

CAS Number

67247-11-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

565.73

Molecular Formula

C27H43N5O6S

Notes

Research use only, not for human use.

Receptor

EC50: 3.5 nM (FPR1), 6.7 μM (FPR2), 0.88 μM (FPR2-D2817.32G)

Available Sizes

Curated Selection

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