Urocortin, human
Urocortin, human, a 40-aa neuropeptide, acts as a selective agonist of endogenous CRF2 receptor, with Kis of 0.4, 0.3, and 0.5 nM for hCRF1, rCRF2α and mCRF2β, respectively. Urocortin human can be used as a test compound for studying the impact of corticotropin-releasing factor (CRF) receptor agonist and antagonist on sleep-wake patterns in conscious rats by using radiotelemetry system.
Product Specifications
CAS Number
176591-49-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
4696.24
Molecular Formula
C204H337N63O64
Notes
Research use only, not for human use.
Receptor
Ki: 0.4 nM (hCRF1, cell assay), 0.3 nM (rCRF2α, cell assay), and 0.5 nM (mCRF2β, cell assay)
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