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NecroX-7 B

NecroX-7 (LC-280126) is a potent free radical scavenger and HMGB1 (high-mobility group box 1) inhibitor. It serves as an antidote to acetaminophen toxicity and exerts a protective effect by preventing HMGB1 release in ischemia/reperfusion injury. Additionally, NecroX-7 inhibits HMGB1-induced release of TNF and IL-6 and the expression of TLR-4 and receptor for advanced glycation end products. This compound may be used for graft-versus-host disease (GVHD) research .

Product Specifications

CAS Number

1120332-55-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

439.57

Molecular Formula

C24H29N3O3S

Notes

Research use only, not for human use.

Receptor

NADPH-oxidase

Available Sizes

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