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AZD-4877

AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .

Product Specifications

CAS Number

758722-49-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

503.66

Molecular Formula

C28H33N5O2S

Notes

Research use only, not for human use.

Receptor

Apoptosis | Kinesin

Available Sizes

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