AZD-4877
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .
Product Specifications
CAS Number
758722-49-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
503.66
Molecular Formula
C28H33N5O2S
Notes
Research use only, not for human use.
Receptor
Apoptosis | Kinesin
Available Sizes
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