IDH2R140Q-IN-2
IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML) .
Product Specifications
CAS Number
2749568-16-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
484.4
Molecular Formula
C21H18F6N6O
Notes
Research use only, not for human use.
Receptor
Dehydrogenase
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
