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IDH2R140Q-IN-2

IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML) .

Product Specifications

CAS Number

2749568-16-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

484.4

Molecular Formula

C21H18F6N6O

Notes

Research use only, not for human use.

Receptor

Dehydrogenase

Available Sizes

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